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The Roles of SPOP in DNA Damage Response and DNA Replication
Speckle-type BTB/POZ protein (SPOP) is a substrate recognition receptor of the cullin-3 (CUL3)/RING type ubiquitin E3 complex. To date, approximately 30 proteins have been identified as ubiquitinated substrates of the CUL3/SPOP complex. Pathologically, missense mutations in the substrate-binding dom...
Autores principales: | Maekawa, Masashi, Higashiyama, Shigeki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582541/ https://www.ncbi.nlm.nih.gov/pubmed/33023230 http://dx.doi.org/10.3390/ijms21197293 |
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