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Allopregnanolone Enhances GABAergic Inhibition in Spinal Motor Networks

The neurosteroid allopregnanolone (ALLO) causes unconsciousness by allosteric modulation of γ-aminobutyric acid type A (GABA(A)) receptors, but its actions on the spinal motor networks are unknown. We are therefore testing the hypothesis that ALLO attenuates the action potential firing of spinal int...

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Detalles Bibliográficos
Autores principales: Drexler, Berthold, Grenz, Julia, Grasshoff, Christian, Antkowiak, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582554/
https://www.ncbi.nlm.nih.gov/pubmed/33036451
http://dx.doi.org/10.3390/ijms21197399