4-Oxatricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione Derivatives as NMDA Receptor- and VGCC Blockers with Neuroprotective Potential

The impact of excitotoxicity mediated by N-methyl-D-aspartate (NMDA) receptor overactivation and voltage gated calcium channel (VGCC) depolarization is prominent among the postulated processes involved in the development of neurodegenerative disorders. NGP1-01, a polycyclic amine, has been shown to...

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Detalles Bibliográficos
Autores principales: Egunlusi, Ayodeji O., Malan, Sarel F., Omoruyi, Sylvester I., Ekpo, Okobi E., Joubert, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582567/
https://www.ncbi.nlm.nih.gov/pubmed/33027964
http://dx.doi.org/10.3390/molecules25194552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582567/
https://www.ncbi.nlm.nih.gov/pubmed/33027964
http://dx.doi.org/10.3390/molecules25194552

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