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What Role Does COA6 Play in Cytochrome C Oxidase Biogenesis: A Metallochaperone or Thiol Oxidoreductase, or Both?

Complex IV (cytochrome c oxidase; COX) is the terminal complex of the mitochondrial electron transport chain. Copper is essential for COX assembly, activity, and stability, and is incorporated into the dinuclear Cu(A) and mononuclear Cu(B) sites. Multiple assembly factors play roles in the biogenesi...

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Detalles Bibliográficos
Autores principales: Maghool, Shadi, Ryan, Michael T., Maher, Megan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582641/
https://www.ncbi.nlm.nih.gov/pubmed/32977416
http://dx.doi.org/10.3390/ijms21196983