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High Mannose N-Glycans Promote Migration of Bone-Marrow-Derived Mesenchymal Stromal Cells

For hundreds of indications, mesenchymal stromal cells (MSCs) have not achieved the expected therapeutic efficacy due to an inability of the cells to reach target tissues. We show that inducing high mannose N-glycans either chemically, using the mannosidase I inhibitor Kifunensine, or genetically, u...

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Detalles Bibliográficos
Autores principales: Alonso-Garcia, Vivian, Chaboya, Cutter, Li, Qiongyu, Le, Bryan, Congleton, Timothy J., Florez, Jose, Tran, Victoria, Liu, Gang-Yu, Yao, Wei, Lebrilla, Carlito B., Fierro, Fernando A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582662/
https://www.ncbi.nlm.nih.gov/pubmed/33003435
http://dx.doi.org/10.3390/ijms21197194