Actions of FTY720 (Fingolimod), a Sphingosine-1-Phosphate Receptor Modulator, on Delayed-Rectifier K(+) Current and Intermediate-Conductance Ca(2+)-Activated K(+) Channel in Jurkat T-Lymphocytes

FTY720 (fingolimod), a modulator of sphingosine-1-phosphate receptors, is known to produce the immunomodulatory actions and to be beneficial for treating the relapsing multiple sclerosis. However, whether it exerts any effects on membrane ion currents in immune cells remains largely unknown. Herein,...

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Detalles Bibliográficos
Autores principales: Chang, Wei-Ting, Liu, Ping-Yen, Wu, Sheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582672/
https://www.ncbi.nlm.nih.gov/pubmed/33023219
http://dx.doi.org/10.3390/molecules25194525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582672/
https://www.ncbi.nlm.nih.gov/pubmed/33023219
http://dx.doi.org/10.3390/molecules25194525

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