The Down-Regulation of Clusterin Expression Enhances the αSynuclein Aggregation Process

Parkinson’s Disease (PD) is a progressive neurodegenerative disease characterized by the presence of proteinaceous aggregates of αSynuclein (αSyn) in the dopaminergic neurons. Chaperones are key components of the proteostasis network that are able to counteract αSyn’s aggregation, as well as its tox...

Descripción completa

Detalles Bibliográficos
Autores principales: Lenzi, Chiara, Ramazzina, Ileana, Russo, Isabella, Filippini, Alice, Bettuzzi, Saverio, Rizzi, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582711/
https://www.ncbi.nlm.nih.gov/pubmed/33003328
http://dx.doi.org/10.3390/ijms21197181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582711/
https://www.ncbi.nlm.nih.gov/pubmed/33003328
http://dx.doi.org/10.3390/ijms21197181

Ejemplares similares