Cargando…

ND-13, a DJ-1-Derived Peptide, Attenuates the Renal Expression of Fibrotic and Inflammatory Markers Associated with Unilateral Ureter Obstruction

DJ-1 is a redox-sensitive chaperone with reported antioxidant and anti-inflammatory properties in the kidney. The 20 amino acid (aa) peptide ND-13 consists of 13 highly conserved aas from the DJ-1 sequence and a TAT-derived 7 aa sequence that helps in cell penetration. This study aimed to determine...

Descripción completa

Detalles Bibliográficos
Autores principales: De Miguel, Carmen, Kraus, Abigayle C., Saludes, Mitchell A., Konkalmatt, Prasad, Ruiz Domínguez, Almudena, Asico, Laureano D., Latham, Patricia S., Offen, Daniel, Jose, Pedro A., Cuevas, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582723/
https://www.ncbi.nlm.nih.gov/pubmed/32987947
http://dx.doi.org/10.3390/ijms21197048