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Soluble Prion Peptide 107–120 Protects Neuroblastoma SH-SY5Y Cells against Oligomers Associated with Alzheimer’s Disease

Alzheimer’s disease (AD) is the most prevalent form of dementia and soluble amyloid β (Aβ) oligomers are thought to play a critical role in AD pathogenesis. Cellular prion protein (PrP(C)) is a high-affinity receptor for Aβ oligomers and mediates some of their toxic effects. The N-terminal region of...

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Detalles Bibliográficos
Autores principales: Rezvani Boroujeni, Elham, Hosseini, Seyed Masoud, Fani, Giulia, Cecchi, Cristina, Chiti, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582777/
https://www.ncbi.nlm.nih.gov/pubmed/33019683
http://dx.doi.org/10.3390/ijms21197273