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Nucleophilic Synthesis of 6-l-[(18)F]FDOPA. Is Copper-Mediated Radiofluorination the Answer?
Positron emission tomography employing 6-l-[(18)F]fluoro-3,4-dihydroxyphenylalanine (6-l-[(18)F]FDOPA) is currently a highly relevant clinical tool for detection of gliomas, neuroendocrine tumors and evaluation of Parkinson’s disease progression. Yet, the deficiencies of electrophilic synthesis of 6...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582790/ https://www.ncbi.nlm.nih.gov/pubmed/32977512 http://dx.doi.org/10.3390/molecules25194365 |