Cellular and Molecular Mechanisms of CD8(+) T Cell Differentiation, Dysfunction and Exhaustion

T cells follow a triphasic distinct pathway of activation, proliferation and differentiation before becoming functionally and phenotypically “exhausted” in settings of chronic infection, autoimmunity and in cancer. Exhausted T cells progressively lose canonical effector functions, exhibit altered tr...

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Detalles Bibliográficos
Autores principales: Verdon, Daniel J., Mulazzani, Matthias, Jenkins, Misty R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582856/
https://www.ncbi.nlm.nih.gov/pubmed/33027962
http://dx.doi.org/10.3390/ijms21197357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582856/
https://www.ncbi.nlm.nih.gov/pubmed/33027962
http://dx.doi.org/10.3390/ijms21197357

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