Sericin-Induced Melanogenesis in Cultured Retinal Pigment Epithelial Cells Is Associated with Elevated Levels of Hydrogen Peroxide and Inflammatory Proteins

We previously demonstrated that the silk protein sericin promotes pigmentation of retinal pigment epithelium (RPE) by activating the NF-κB pathway. Among numerous agents, NF-κB can be activated by hydrogen peroxide. In the present study, we explored possible associations between reactive oxygen spec...

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Detalles Bibliográficos
Autores principales: Khan, Ayyad Zartasht, Jackson, Catherine Joan, Utheim, Tor Paaske, Reppe, Sjur, Sapkota, Dipak, Olstad, Ole Kristoffer, Thiede, Bernd, Eidet, Jon Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582875/
https://www.ncbi.nlm.nih.gov/pubmed/32987810
http://dx.doi.org/10.3390/molecules25194395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582875/
https://www.ncbi.nlm.nih.gov/pubmed/32987810
http://dx.doi.org/10.3390/molecules25194395

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