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Sericin-Induced Melanogenesis in Cultured Retinal Pigment Epithelial Cells Is Associated with Elevated Levels of Hydrogen Peroxide and Inflammatory Proteins
We previously demonstrated that the silk protein sericin promotes pigmentation of retinal pigment epithelium (RPE) by activating the NF-κB pathway. Among numerous agents, NF-κB can be activated by hydrogen peroxide. In the present study, we explored possible associations between reactive oxygen spec...
Autores principales: | Khan, Ayyad Zartasht, Jackson, Catherine Joan, Utheim, Tor Paaske, Reppe, Sjur, Sapkota, Dipak, Olstad, Ole Kristoffer, Thiede, Bernd, Eidet, Jon Roger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582875/ https://www.ncbi.nlm.nih.gov/pubmed/32987810 http://dx.doi.org/10.3390/molecules25194395 |
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