Recombinant Tissue Plasminogen Activator (r-tPA) Induces In-Vitro Human Neutrophil Migration via Low Density Lipoprotein Receptor-Related Protein 1 (LRP-1)

Thrombolysis is the gold standard treatment for acute ischemic stroke. Besides its fibrinolytic role, recombinant tissue plasminogen activator (r-tPA) holds several non-fibrinolytic functions. Here, we investigated the potential role of r-tPA on human primary neutrophil migration in vitro. By means...

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Detalles Bibliográficos
Autores principales: Liberale, Luca, Bertolotto, Maria, Minetti, Silvia, Contini, Paola, Verzola, Daniela, Ameri, Pietro, Ghigliotti, Giorgio, Pende, Aldo, Camici, Giovanni G., Carbone, Federico, Montecucco, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582901/
https://www.ncbi.nlm.nih.gov/pubmed/32977685
http://dx.doi.org/10.3390/ijms21197014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582901/
https://www.ncbi.nlm.nih.gov/pubmed/32977685
http://dx.doi.org/10.3390/ijms21197014

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