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Characterization of Cetacean Proline-Rich Antimicrobial Peptides Displaying Activity against ESKAPE Pathogens

Proline-rich antimicrobial peptides (PrAMPs) may be a valuable weapon against multi-drug resistant pathogens, combining potent antimicrobial activity with low cytotoxicity. We have identified novel PrAMPs from five cetacean species (cePrAMPs), and characterized their potency, mechanism of action and...

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Detalles Bibliográficos
Autores principales: Sola, Riccardo, Mardirossian, Mario, Beckert, Bertrand, Sanghez De Luna, Laura, Prickett, Dennis, Tossi, Alessandro, Wilson, Daniel N., Scocchi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582929/
https://www.ncbi.nlm.nih.gov/pubmed/33036159
http://dx.doi.org/10.3390/ijms21197367