Synthesis of New Imidazopyridine Nucleoside Derivatives Designed as Maribavir Analogues

The strong inhibition of Human Cytomegalovirus (HCMV) replication by benzimidazole nucleosides, like Triciribine and Maribavir, has prompted us to expand the structure–activity relationships of the benzimidazole series, using as a central core the imidazo[4,5-b]pyridine scaffold. We have thus synthe...

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Detalles Bibliográficos
Autores principales: Papadakis, Georgios, Gerasi, Maria, Snoeck, Robert, Marakos, Panagiotis, Andrei, Graciela, Lougiakis, Nikolaos, Pouli, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582934/
https://www.ncbi.nlm.nih.gov/pubmed/33022923
http://dx.doi.org/10.3390/molecules25194531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582934/
https://www.ncbi.nlm.nih.gov/pubmed/33022923
http://dx.doi.org/10.3390/molecules25194531

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