MKP-5 Relieves Lipotoxicity-Induced Islet β-Cell Dysfunction and Apoptosis via Regulation of Autophagy

Mitogen-activated protein kinase phosphatase-5 (MKP-5) is a regulator of extracellular signaling that is known to regulate lipid metabolism. In this study, we found that obesity caused by a high-fat diet (HFD) decreased the expression of MKP-5 in the pancreas and primary islet cells derived from mic...

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Detalles Bibliográficos
Autores principales: Zhao, Tongjian, Ma, Jie, Li, Lulu, Teng, Wenjing, Tian, Yafei, Ma, Yongjun, Wang, Wei, Yan, Weiqun, Jiao, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582937/
https://www.ncbi.nlm.nih.gov/pubmed/32998359
http://dx.doi.org/10.3390/ijms21197161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582937/
https://www.ncbi.nlm.nih.gov/pubmed/32998359
http://dx.doi.org/10.3390/ijms21197161

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