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Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors

Ly-6/uPAR or three-finger proteins (TFPs) contain a disulfide-stabilized β-structural core and three protruding loops (fingers). In mammals, TFPs have been found in epithelium and the nervous, endocrine, reproductive, and immune systems. Here, using heteronuclear NMR, we determined the three-dimensi...

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Detalles Bibliográficos
Autores principales: Paramonov, Alexander S., Kocharovskaya, Milita V., Tsarev, Andrey V., Kulbatskii, Dmitrii S., Loktyushov, Eugene V., Shulepko, Mikhail A., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N., Shenkarev, Zakhar O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582953/
https://www.ncbi.nlm.nih.gov/pubmed/33019770
http://dx.doi.org/10.3390/ijms21197280