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Amphiphilic Aminoglycosides as Medicinal Agents

The conjugation of hydrophobic group(s) to the polycationic hydrophilic core of the antibiotic drugs aminoglycosides (AGs), targeting ribosomal RNA, has led to the development of amphiphilic aminoglycosides (AAGs). These drugs exhibit numerous biological effects, including good antibacterial effects...

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Detalles Bibliográficos
Autores principales: Dezanet, Clément, Kempf, Julie, Mingeot-Leclercq, Marie-Paule, Décout, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583001/
https://www.ncbi.nlm.nih.gov/pubmed/33049963
http://dx.doi.org/10.3390/ijms21197411