Spatial and Temporal Changes in PD-L1 Expression in Cancer: The Role of Genetic Drivers, Tumor Microenvironment and Resistance to Therapy

Immunotherapies blocking immune inhibitory receptors programmed cell death-1 (PD-1) and cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) on T-cells have dramatically improved patient outcomes in a range of advanced cancers. However, the lack of response, and the development of resistance remain...

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Detalles Bibliográficos
Autores principales: Shklovskaya, Elena, Rizos, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583014/
https://www.ncbi.nlm.nih.gov/pubmed/32992658
http://dx.doi.org/10.3390/ijms21197139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583014/
https://www.ncbi.nlm.nih.gov/pubmed/32992658
http://dx.doi.org/10.3390/ijms21197139

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