Biphasic Force-Regulated Phosphorylation Site Exposure and Unligation of ERM Bound with PSGL-1: A Novel Insight into PSGL-1 Signaling via Steered Molecular Dynamics Simulations

The PSGL-1-actin cytoskeleton linker proteins ezrin/radixin/moesin (ERM), an adaptor between P-selectin glycoprotein ligand-1 (PSGL-1) and spleen tyrosine kinase (Syk), is a key player in PSGL-1 signal, which mediates the adhesion and recruitment of leukocytes to the activated endothelial cells in f...

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Detalles Bibliográficos
Autores principales: Feng, Jingjing, Zhang, Yan, Li, Quhuan, Fang, Ying, Wu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583015/
https://www.ncbi.nlm.nih.gov/pubmed/32992803
http://dx.doi.org/10.3390/ijms21197064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583015/
https://www.ncbi.nlm.nih.gov/pubmed/32992803
http://dx.doi.org/10.3390/ijms21197064

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