GPAT Gene Silencing in Muscle Reduces Diacylglycerols Content and Improves Insulin Action in Diet-Induced Insulin Resistance

Skeletal muscle is an important tissue responsible for glucose and lipid metabolism. High-fat diet (HFD) consumption is associated with the accumulation of bioactive lipids: long chain acyl-CoA, diacylglycerols (DAG) and ceramides. This leads to impaired insulin signaling in skeletal muscle. There i...

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Detalles Bibliográficos
Autores principales: Kojta, Iwona, Zabielski, Piotr, Roszczyc-Owsiejczuk, Kamila, Imierska, Monika, Sokołowska, Emilia, Błachnio-Zabielska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583033/
https://www.ncbi.nlm.nih.gov/pubmed/33036203
http://dx.doi.org/10.3390/ijms21197369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583033/
https://www.ncbi.nlm.nih.gov/pubmed/33036203
http://dx.doi.org/10.3390/ijms21197369

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