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The Interaction of Innate and Adaptive Immunity and Stabilization of Mast Cell Activation in Management of Infusion Related Reactions in Patients with Fabry Disease

Fabry disease (FD) is an X-linked lysosomal disorder caused by mutations in GLA gene resulting in lack of or faulty α-galactosidase A (α-GalA) enzyme. Enzyme replacement therapy (ERT) with recombinant human α-GalA enzyme (agalsidase) is the standard treatment option for FD. Infusion-related reaction...

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Detalles Bibliográficos
Autores principales: Limgala, Renuka P., Fikry, Jaqueline, Veligatla, Vasudha, Goker-Alpan, Ozlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583043/
https://www.ncbi.nlm.nih.gov/pubmed/33003611
http://dx.doi.org/10.3390/ijms21197213