Cargando…

Changes in the frequencies of Plasmodium falciparum dhps and dhfr drug-resistant mutations in children from Western Kenya from 2005 to 2018: the rise of Pfdhps S436H

BACKGROUND: Sulfadoxine-pyrimethamine (SP) is the only anti-malarial drug formulation approved for intermittent preventive treatment in pregnancy (IPTp). However, mutations in the Plasmodium falciparum dhfr (Pfdhfr) and dhps (Pfdhps) genes confer resistance to pyrimethamine and sulfadoxine, respecti...

Descripción completa

Detalles Bibliográficos
Autores principales: Pacheco, M. Andreína, Schneider, Kristan A., Cheng, Qiuying, Munde, Elly O., Ndege, Caroline, Onyango, Clinton, Raballah, Evans, Anyona, Samuel B., Ouma, Collins, Perkins, Douglas J., Escalante, Ananias A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583259/
https://www.ncbi.nlm.nih.gov/pubmed/33092587
http://dx.doi.org/10.1186/s12936-020-03454-8