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Changes in the frequencies of Plasmodium falciparum dhps and dhfr drug-resistant mutations in children from Western Kenya from 2005 to 2018: the rise of Pfdhps S436H

BACKGROUND: Sulfadoxine-pyrimethamine (SP) is the only anti-malarial drug formulation approved for intermittent preventive treatment in pregnancy (IPTp). However, mutations in the Plasmodium falciparum dhfr (Pfdhfr) and dhps (Pfdhps) genes confer resistance to pyrimethamine and sulfadoxine, respecti...

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Detalles Bibliográficos
Autores principales:	Pacheco, M. Andreína, Schneider, Kristan A., Cheng, Qiuying, Munde, Elly O., Ndege, Caroline, Onyango, Clinton, Raballah, Evans, Anyona, Samuel B., Ouma, Collins, Perkins, Douglas J., Escalante, Ananias A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583259/ https://www.ncbi.nlm.nih.gov/pubmed/33092587 http://dx.doi.org/10.1186/s12936-020-03454-8

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