Yes-associated protein (YAP) induces a secretome phenotype and transcriptionally regulates plasminogen activator Inhibitor-1 (PAI-1) expression in hepatocarcinogenesis

BACKGROUND: Overexpression and nuclear enrichment of the oncogene yes-associated protein (YAP) cause tumor initiation and support tumor progression in human hepatocellular carcinoma (HCC) via cell autonomous mechanisms. However, how YAP expression in tumor cells affects intercellular communication w...

Descripción completa

Detalles Bibliográficos
Autores principales: Marquard, Simone, Thomann, Stefan, Weiler, Sofia M. E., Bissinger, Michaela, Lutz, Teresa, Sticht, Carsten, Tóth, Marcell, de la Torre, Carolina, Gretz, Norbert, Straub, Beate K., Marquardt, Jens, Schirmacher, Peter, Breuhahn, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583285/
https://www.ncbi.nlm.nih.gov/pubmed/33097058
http://dx.doi.org/10.1186/s12964-020-00634-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583285/
https://www.ncbi.nlm.nih.gov/pubmed/33097058
http://dx.doi.org/10.1186/s12964-020-00634-6

Ejemplares similares