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Co-encapsulation of HNF4α overexpressing UMSCs and human primary hepatocytes ameliorates mouse acute liver failure

BACKGROUND: Acute liver failure (ALF) is a complicated condition that is characterized by global hepatocyte death and often requires immediate liver transplantation. However, this therapy is limited by shortage of donor organs. Mesenchymal stem cells (MSCs) and hepatocytes are two attractive sources...

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Detalles Bibliográficos
Autores principales: Kong, Defu, Xu, Huiming, Chen, Mo, Yu, Yeping, Qian, Yongbing, Qin, Tian, Tong, Ying, Xia, Qiang, Hang, Hualian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583302/
https://www.ncbi.nlm.nih.gov/pubmed/33097090
http://dx.doi.org/10.1186/s13287-020-01962-7