Interaction of small molecules with the SARS-CoV-2 main protease in silico and in vitro validation of potential lead compounds using an enzyme-linked immunosorbent assay

Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the COVID-19 pandemic is ongoing, with no proven safe and effective vaccine to date. Further, effective therapeutic agents for COVID-19 are limited, and as a result, the identification of potential small molecule antiviral d...

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Detalles Bibliográficos
Autores principales: Pitsillou, Eleni, Liang, Julia, Karagiannis, Chris, Ververis, Katherine, Darmawan, Kevion K., Ng, Ken, Hung, Andrew, Karagiannis, Tom C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583591/
https://www.ncbi.nlm.nih.gov/pubmed/33137690
http://dx.doi.org/10.1016/j.compbiolchem.2020.107408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583591/
https://www.ncbi.nlm.nih.gov/pubmed/33137690
http://dx.doi.org/10.1016/j.compbiolchem.2020.107408

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