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Interaction of small molecules with the SARS-CoV-2 main protease in silico and in vitro validation of potential lead compounds using an enzyme-linked immunosorbent assay

Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the COVID-19 pandemic is ongoing, with no proven safe and effective vaccine to date. Further, effective therapeutic agents for COVID-19 are limited, and as a result, the identification of potential small molecule antiviral d...

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Detalles Bibliográficos
Autores principales:	Pitsillou, Eleni, Liang, Julia, Karagiannis, Chris, Ververis, Katherine, Darmawan, Kevion K., Ng, Ken, Hung, Andrew, Karagiannis, Tom C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583591/ https://www.ncbi.nlm.nih.gov/pubmed/33137690 http://dx.doi.org/10.1016/j.compbiolchem.2020.107408

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