Evaluation of Single-Cell Cytokine Secretion and Cell-Cell Interactions with a Hierarchical Loading Microwell Chip

Comprehensive evaluation of single T cell functions such as cytokine secretion and cytolysis of target cells is greatly needed in adoptive cell therapy (ACT) but has never been fully fulfilled by current approaches. Herein, we develop a hierarchical loading microwell chip (HL-Chip) that aligns multi...

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Detalles Bibliográficos
Autores principales: Zhou, Yufu, Shao, Ning, de Castro, Ricardo Bessa, Zhang, Pengchao, Ma, Yuan, Liu, Xin, Huang, Feizhou, Wang, Rong-Fu, Qin, Lidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583657/
https://www.ncbi.nlm.nih.gov/pubmed/32348757
http://dx.doi.org/10.1016/j.celrep.2020.107574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583657/
https://www.ncbi.nlm.nih.gov/pubmed/32348757
http://dx.doi.org/10.1016/j.celrep.2020.107574

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