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Interplay Between NLRP3 Inflammasome and Autophagy

The NLRP3 inflammasome is cytosolic multi-protein complex that induces inflammation and pyroptotic cell death in response to both pathogen (PAMPs) and endogenous activators (DAMPs). Recognition of PAMPs or DAMPs leads to formation of the inflammasome complex, which results in activation of caspase-1...

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Detalles Bibliográficos
Autores principales: Biasizzo, Monika, Kopitar-Jerala, Nataša
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583715/
https://www.ncbi.nlm.nih.gov/pubmed/33163006
http://dx.doi.org/10.3389/fimmu.2020.591803