Gap19, a Cx43 Hemichannel Inhibitor, Acts as a Gating Modifier That Decreases Main State Opening While Increasing Substate Gating

Cx43 hemichannels (HCs) are electrically and chemically gated transmembrane pores with low open probability and multiple conductance states, which makes kinetic studies of channel gating in large datasets challenging. Here, we developed open access software, named HemiGUI, to analyze HC gating trans...

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Detalles Bibliográficos
Autores principales: Lissoni, Alessio, Wang, Nan, Nezlobinskii, Timur, De Smet, Maarten, Panfilov, Alexander V., Vandersickel, Nele, Leybaert, Luc, Witschas, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583728/
https://www.ncbi.nlm.nih.gov/pubmed/33027889
http://dx.doi.org/10.3390/ijms21197340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583728/
https://www.ncbi.nlm.nih.gov/pubmed/33027889
http://dx.doi.org/10.3390/ijms21197340

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