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miR-451a suppression of IL-6R can inhibit proliferation and increase apoptosis through the JAK2/STAT3 pathway in multiple myeloma

The IL-6R/JAK2/STAT3 pathway mediated by interleukin-6 (IL-6) plays an important role in the occurrence and development of multiple myeloma (MM), which is associated with decreased microRNA-451a. However, the biological function of microRNA-451a in MM remains unclear. The bone marrow (BM) of patient...

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Detalles Bibliográficos
Autores principales: Zhong, Ling, Xu, Zhuyu, Jin, Xin, He, Yuan, Zhang, Jianbo, Jiang, Tao, Chen, Jiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583731/
https://www.ncbi.nlm.nih.gov/pubmed/33123250
http://dx.doi.org/10.3892/ol.2020.12202