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miR-451a suppression of IL-6R can inhibit proliferation and increase apoptosis through the JAK2/STAT3 pathway in multiple myeloma
The IL-6R/JAK2/STAT3 pathway mediated by interleukin-6 (IL-6) plays an important role in the occurrence and development of multiple myeloma (MM), which is associated with decreased microRNA-451a. However, the biological function of microRNA-451a in MM remains unclear. The bone marrow (BM) of patient...
Autores principales: | Zhong, Ling, Xu, Zhuyu, Jin, Xin, He, Yuan, Zhang, Jianbo, Jiang, Tao, Chen, Jiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583731/ https://www.ncbi.nlm.nih.gov/pubmed/33123250 http://dx.doi.org/10.3892/ol.2020.12202 |
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