A Working Hypothesis Regarding Identical Pathomechanisms between Clinical Efficacy and Adverse Reaction of Clozapine via the Activation of Connexin43

Clozapine (CLZ) is an approved antipsychotic agent for the medication of treatment-resistant schizophrenia but is also well known as one of the most toxic antipsychotics. Recently, the World Health Organization’s (WHO) global database (VigiBase) reported the relative lethality of severe adverse reac...

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Detalles Bibliográficos
Autores principales: Okada, Motohiro, Fukuyama, Kouji, Shiroyama, Takashi, Murata, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583770/
https://www.ncbi.nlm.nih.gov/pubmed/32987640
http://dx.doi.org/10.3390/ijms21197019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583770/
https://www.ncbi.nlm.nih.gov/pubmed/32987640
http://dx.doi.org/10.3390/ijms21197019

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