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Investigation of a Pharmacological Approach for Reduction of Renal Uptake of Radiolabeled ADAPT Scaffold Protein

Albumin binding domain-Derived Affinity ProTeins (ADAPTs) are small (5 kDa) engineered scaffold proteins that are promising targeting agents for radionuclide-based imaging. A recent clinical study has demonstrated that radiolabeled ADAPTs can efficiently visualize human epidermal growth factor recep...

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Detalles Bibliográficos
Autores principales: Vorobyeva, Anzhelika, Oroujeni, Maryam, Lindbo, Sarah, Hober, Sophia, Xu, Tianqi, Liu, Yongsheng, Rinne, Sara S., Garousi, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583817/
https://www.ncbi.nlm.nih.gov/pubmed/32998229
http://dx.doi.org/10.3390/molecules25194448