Initial In Vitro and In Vivo Evaluation of a Novel CCK2R Targeting Peptide Analog Labeled with Lutetium-177

Targeting of cholecystokinin-2 receptor (CCK2R) expressing tumors using radiolabeled minigastrin (MG) analogs is hampered by rapid digestion of the linear peptide in vivo. In this study, a new MG analog stabilized against enzymatic degradation was investigated in preclinical studies to characterize...

Descripción completa

Detalles Bibliográficos
Autores principales: Hörmann, Anton Amadeus, Klingler, Maximilian, Rezaeianpour, Maliheh, Hörmann, Nikolas, Gust, Ronald, Shahhosseini, Soraya, von Guggenberg, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583830/
https://www.ncbi.nlm.nih.gov/pubmed/33049999
http://dx.doi.org/10.3390/molecules25194585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583830/
https://www.ncbi.nlm.nih.gov/pubmed/33049999
http://dx.doi.org/10.3390/molecules25194585

Ejemplares similares