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Enhanced Internalization of Nanoparticles Following Ionizing Radiation Leads to Mitotic Catastrophe in MG-63 Human Osteosarcoma Cells

This study aims to investigate whether ionizing radiation combined with doxorubicin-conjugated iron oxide nanoparticles (NP-DOX) improves the internalization and cytotoxic effects of the nano-carrier-mediated drug delivery in MG-63 human osteosarcoma cells. NP-DOX was designed and synthesized using...

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Detalles Bibliográficos
Autores principales: Popescu, Roxana Cristina, Straticiuc, Mihai, Mustăciosu, Cosmin, Temelie, Mihaela, Trușcă, Roxana, Vasile, Bogdan Ștefan, Boldeiu, Adina, Mirea, Dragoş, Andrei, Radu Florin, Cenușă, Constantin, Mogoantă, Laurenţiu, Mogoșanu, George Dan, Andronescu, Ecaterina, Radu, Mihai, Veldwijk, Marlon R., Savu, Diana Iulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583846/
https://www.ncbi.nlm.nih.gov/pubmed/33007844
http://dx.doi.org/10.3390/ijms21197220