Cargando…

Enhanced Internalization of Nanoparticles Following Ionizing Radiation Leads to Mitotic Catastrophe in MG-63 Human Osteosarcoma Cells

This study aims to investigate whether ionizing radiation combined with doxorubicin-conjugated iron oxide nanoparticles (NP-DOX) improves the internalization and cytotoxic effects of the nano-carrier-mediated drug delivery in MG-63 human osteosarcoma cells. NP-DOX was designed and synthesized using...

Descripción completa

Detalles Bibliográficos
Autores principales:	Popescu, Roxana Cristina, Straticiuc, Mihai, Mustăciosu, Cosmin, Temelie, Mihaela, Trușcă, Roxana, Vasile, Bogdan Ștefan, Boldeiu, Adina, Mirea, Dragoş, Andrei, Radu Florin, Cenușă, Constantin, Mogoantă, Laurenţiu, Mogoșanu, George Dan, Andronescu, Ecaterina, Radu, Mihai, Veldwijk, Marlon R., Savu, Diana Iulia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583846/ https://www.ncbi.nlm.nih.gov/pubmed/33007844 http://dx.doi.org/10.3390/ijms21197220

Ejemplares similares

Fabrication and Cytotoxicity of Gemcitabine-Functionalized Magnetite Nanoparticles
por: Popescu, Roxana Cristina, et al.
Publicado: (2017)

Influence of Polymer Shell Molecular Weight on Functionalized Iron Oxide Nanoparticles Morphology and In Vivo Biodistribution
por: Popescu, Roxana Cristina, et al.
Publicado: (2022)

Antibiofilm Coatings Based on PLGA and Nanostructured Cefepime-Functionalized Magnetite
por: Ficai, Denisa, et al.
Publicado: (2018)

Multifunctional Platforms Based on Graphene Oxide and Natural Products
por: Croitoru, Alexa, et al.
Publicado: (2019)

Silver Nanocoatings for Reducing the Exogenous Microbial Colonization of Wound Dressings
por: Radulescu, Marius, et al.
Publicado: (2016)

Biodistribution of essential oil-conjugated silver nanoparticles
por: Gherasim, Oana, et al.
Publicado: (2020)

MAPLE Coatings Embedded with Essential Oil-Conjugated Magnetite for Anti-Biofilm Applications
por: Gherasim, Oana, et al.
Publicado: (2021)

RNA-Binding Proteins HuB, HuC, and HuD are Distinctly Regulated in Dorsal Root Ganglia Neurons from STZ-Sensitive Compared to STZ-Resistant Diabetic Mice
por: Mustăciosu, Cosmin Cătălin, et al.
Publicado: (2019)

Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview
por: Burdușel, Alexandra-Cristina, et al.
Publicado: (2018)

Efficient uptake and retention of iron oxide-based nanoparticles in HeLa cells leads to an effective intracellular delivery of doxorubicin
por: Popescu, R. C., et al.
Publicado: (2020)

Nanoparticle-Mediated Drug Delivery of Doxorubicin Induces a Differentiated Clonogenic Inactivation in 3D Tumor Spheroids In Vitro
por: Popescu, Roxana Cristina, et al.
Publicado: (2023)

Intracellular Delivery of Doxorubicin by Iron Oxide-Based Nano-Constructs Increases Clonogenic Inactivation of Ionizing Radiation in HeLa Cells
por: Popescu, Roxana Cristina, et al.
Publicado: (2021)

Synthesis and Characterization of Photoluminescent Ce(III) and Ce(IV) Substituted Hydroxyapatite Nanomaterials by Co-Precipitation Method: Cytotoxicity and Biocompatibility Evaluation
por: Paduraru, Andrei Viorel, et al.
Publicado: (2021)

Fabrication, Characterization, and Evaluation of Bionanocomposites Based on Natural Polymers and Antibiotics for Wound Healing Applications
por: Rădulescu, Marius, et al.
Publicado: (2016)

Impaired Integrated Stress Response and Mitochondrial Integrity Modulate Genotoxic Stress Impact and Lower the Threshold for Immune Signalling
por: Temelie, Mihaela, et al.
Publicado: (2023)

Piezoelectric Biocomposites for Bone Grafting in Dentistry
por: Dumitrescu, Cristina Rodica, et al.
Publicado: (2023)

Chitosan/Graphene Oxide Nanocomposite Membranes as Adsorbents with Applications in Water Purification
por: Croitoru, Alexa-Maria, et al.
Publicado: (2020)

Biodegradable Alginate Films with ZnO Nanoparticles and Citronella Essential Oil—A Novel Antimicrobial Structure
por: Motelica, Ludmila, et al.
Publicado: (2021)

Nanobiomaterials Used in Cancer Therapy: An Up-To-Date Overview
por: Lungu, Iulia Ioana, et al.
Publicado: (2019)

Innovative Antimicrobial Chitosan/ZnO/Ag NPs/Citronella Essential Oil Nanocomposite—Potential Coating for Grapes
por: Motelica, Ludmila, et al.
Publicado: (2020)

Beta-Estradiol Regulates Voltage-Gated Calcium Channels and Estrogen Receptors in Telocytes from Human Myometrium
por: Banciu, Adela, et al.
Publicado: (2018)

Bioactive ZnO Coatings Deposited by MAPLE—An Appropriate Strategy to Produce Efficient Anti-Biofilm Surfaces
por: Oprea, Alexandra Elena, et al.
Publicado: (2016)

Advanced Drug-Eluting Poly (Vinyl Chloride) Surfaces Deposited by Spin Coating
por: Duta, Oana Cristina, et al.
Publicado: (2019)

Usnic Acid-Loaded Magnetite Nanoparticles—A Comparative Study between Synthesis Methods
por: Chircov, Cristina, et al.
Publicado: (2023)

Nanostructures for drug delivery
por: Andronescu, Ecaterina, et al.
Publicado: (2017)

Radiofrequency EMF irradiation effects on pre-B lymphocytes undergoing somatic recombination
por: Ioniţă, Elena, et al.
Publicado: (2021)

Optimal Cardiac Resynchronization Therapy with Conduction System Pacing Guided by Electro-Anatomical Mapping: A Case Report
por: Pestrea, Catalin, et al.
Publicado: (2023)

Intracellular and Intercellular Signalling Mechanisms following DNA Damage Are Modulated By PINK1
por: Temelie, Mihaela, et al.
Publicado: (2018)

Biofilm-Resistant Nanocoatings Based on ZnO Nanoparticles and Linalool
por: Spirescu, Vera Alexandra, et al.
Publicado: (2021)

Recent Advances in Magnetite Nanoparticle Functionalization for Nanomedicine
por: Popescu, Roxana Cristina, et al.
Publicado: (2019)

Modifications in cellular viability, DNA damage and stress responses inflicted in cancer cells by copper-64 ions
por: Serban, Radu M., et al.
Publicado: (2023)

Bi(1−x)Eu(x)FeO(3) Powders: Synthesis, Characterization, Magnetic and Photoluminescence Properties
por: Surdu, Vasile-Adrian, et al.
Publicado: (2019)

Alkali Niobate Powder Synthesis Using an Emerging Microwave-Assisted Hydrothermal Method
por: Dumitrescu, Cristina-Rodica, et al.
Publicado: (2022)

New Mesoporous Silica Materials Loaded with Polyphenols: Caffeic Acid, Ferulic Acid and p-Coumaric Acid as Dietary Supplements for Oral Administration
por: Petrisor, Gabriela, et al.
Publicado: (2022)

Assessment of Properties and Microstructure of Concrete with Cotton Textile Waste and Crushed Bricks
por: Saca, Nastasia, et al.
Publicado: (2023)

Preparation and Preliminary Evaluation of Neurotensin Radiolabelled with (68)Ga and (177)Lu as Potential Theranostic Agent for Colon Cancer
por: Leonte, Radu Anton, et al.
Publicado: (2021)

Biocompatible Fe(3)O(4) Increases the Efficacy of Amoxicillin Delivery against Gram-Positive and Gram-Negative Bacteria
por: Grumezescu, Alexandru Mihai, et al.
Publicado: (2014)

Nano-Hydroxyapatite vs. Xenografts: Synthesis, Characterization, and In Vitro Behavior
por: Dumitrescu, Cristina Rodica, et al.
Publicado: (2021)

Biomimetic Collagen/Zn(2+)-Substituted Calcium Phosphate Composite Coatings on Titanium Substrates as Prospective Bioactive Layer for Implants: A Comparative Study Spin Coating vs. MAPLE
por: Neacsu, Ionela Andreea, et al.
Publicado: (2019)

Collagen/Chitosan Functionalization of Complex 3D Structures Fabricated by Laser Direct Writing via Two-Photon Polymerization for Enhanced Osteogenesis
por: Păun, Irina Alexandra, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4s5b291qqr6drvmhgvujmkgr9h