Solvent Deuterium Oxide Isotope Effects on the Reactions of Organophosphorylated Acetylcholinesterase †

Organophosphates (OPs) are esters of substituted phosphates, phosphonates or phosphoramidates that react with acetylcholinesterase (AChE) by initially transferring the organophosphityl group to a serine residue in the enzyme active site, concomitant with loss of an alcohol or halide leaving group. W...

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Detalles Bibliográficos
Autor principal: Rosenberry, Terrone L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583889/
https://www.ncbi.nlm.nih.gov/pubmed/32992925
http://dx.doi.org/10.3390/molecules25194412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583889/
https://www.ncbi.nlm.nih.gov/pubmed/32992925
http://dx.doi.org/10.3390/molecules25194412

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