Novel Harmicines with Improved Potency against Plasmodium

Harmicines represent hybrid compounds composed of β-carboline alkaloid harmine and cinnamic acid derivatives (CADs). In this paper we report the synthesis of amide-type harmicines and the evaluation of their biological activity. N-harmicines 5a–f and O-harmicines 6a–h were prepared by a straightforw...

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Detalles Bibliográficos
Autores principales: Marinović, Marina, Perković, Ivana, Fontinha, Diana, Prudêncio, Miguel, Held, Jana, Pessanha de Carvalho, Lais, Tandarić, Tana, Vianello, Robert, Zorc, Branka, Rajić, Zrinka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583898/
https://www.ncbi.nlm.nih.gov/pubmed/32977642
http://dx.doi.org/10.3390/molecules25194376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583898/
https://www.ncbi.nlm.nih.gov/pubmed/32977642
http://dx.doi.org/10.3390/molecules25194376

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