Functional Recovery of a GCDH Variant Associated to Severe Deflavinylation—Molecular Insights into Potential Beneficial Effects of Riboflavin Supplementation in Glutaric Aciduria-Type I Patients

Riboflavin is the biological precursor of two important flavin cofactors—flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN)—that are critical prosthetic groups in several redox enzymes. While dietary supplementation with riboflavin is a recognized support therapy in several inborn err...

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Detalles Bibliográficos
Autores principales: Ribeiro, Joana V., Gomes, Cláudio M., Henriques, Bárbara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583906/
https://www.ncbi.nlm.nih.gov/pubmed/32992790
http://dx.doi.org/10.3390/ijms21197063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583906/
https://www.ncbi.nlm.nih.gov/pubmed/32992790
http://dx.doi.org/10.3390/ijms21197063

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