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PKM2 Determines Myofiber Hypertrophy In Vitro and Increases in Response to Resistance Exercise in Human Skeletal Muscle

Nearly 100 years ago, Otto Warburg investigated the metabolism of growing tissues and discovered that tumors reprogram their metabolism. It is poorly understood whether and how hypertrophying muscle, another growing tissue, reprograms its metabolism too. Here, we studied pyruvate kinase muscle (PKM)...

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Detalles Bibliográficos
Autores principales: Verbrugge, Sander A. J., Gehlert, Sebastian, Stadhouders, Lian E. M., Jacko, Daniel, Aussieker, Thorben, M. J. de Wit, Gerard, Vogel, Ilse S. P., Offringa, Carla, Schönfelder, Martin, Jaspers, Richard T., Wackerhage, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583908/
https://www.ncbi.nlm.nih.gov/pubmed/32992783
http://dx.doi.org/10.3390/ijms21197062