Injectable Thermo-Sensitive Chitosan Hydrogel Containing CPT-11-Loaded EGFR-Targeted Graphene Oxide and SLP2 shRNA for Localized Drug/Gene Delivery in Glioblastoma Therapy

In this study, we aimed to develop a multifunctional drug/gene delivery system for the treatment of glioblastoma multiforme by combining the ligand-mediated active targeting and the pH-triggered drug release features of graphene oxide (GO). Toward this end, we load irinotecan (CPT-11) to cetuximab (...

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Detalles Bibliográficos
Autores principales: Lu, Yu-Jen, Lan, Yu-Hsiang, Chuang, Chi-Cheng, Lu, Wan-Ting, Chan, Li-Yang, Hsu, Peng-Wei, Chen, Jyh-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583917/
https://www.ncbi.nlm.nih.gov/pubmed/32993166
http://dx.doi.org/10.3390/ijms21197111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583917/
https://www.ncbi.nlm.nih.gov/pubmed/32993166
http://dx.doi.org/10.3390/ijms21197111

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