How Does Replacement of the Axial Histidine Ligand in Cytochrome c Peroxidase by N(δ)-Methyl Histidine Affect Its Properties and Functions? A Computational Study

Heme peroxidases have important functions in nature related to the detoxification of H(2)O(2). They generally undergo a catalytic cycle where, in the first stage, the iron(III)–heme–H(2)O(2) complex is converted into an iron(IV)–oxo–heme cation radical species called Compound I. Cytochrome c peroxid...

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Detalles Bibliográficos
Autores principales: Lee, Calvin W. Z., Mubarak, M. Qadri E., Green, Anthony P., de Visser, Sam P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583937/
https://www.ncbi.nlm.nih.gov/pubmed/32992593
http://dx.doi.org/10.3390/ijms21197133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583937/
https://www.ncbi.nlm.nih.gov/pubmed/32992593
http://dx.doi.org/10.3390/ijms21197133

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