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Long Noncoding RNA PVT1 Is Regulated by Bromodomain Protein BRD4 in Multiple Myeloma and Is Associated with Disease Progression

Long noncoding RNAs (lncRNAs) are deregulated in human cancers and are associated with disease progression. Plasmacytoma Variant Translocation 1 (PVT1), a lncRNA, is located adjacent to the gene MYC, which has been linked to multiple myeloma (MM). PVT1 is expressed in MM and is associated with carci...

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Detalles Bibliográficos
Autores principales: Handa, Hiroshi, Honma, Kazuki, Oda, Tsukasa, Kobayashi, Nobuhiko, Kuroda, Yuko, Kimura-Masuda, Kei, Watanabe, Saki, Ishihara, Rei, Murakami, Yuki, Masuda, Yuta, Tahara, Ken-ichi, Takei, Hisashi, Kasamatsu, Tetsuhiro, Saitoh, Takayuki, Murakami, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583953/
https://www.ncbi.nlm.nih.gov/pubmed/32992461
http://dx.doi.org/10.3390/ijms21197121