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Structural and Functional Aspects of Targeting the Secreted Human Group IIA Phospholipase A(2)

Human group IIA secretory phospholipase A(2) (hGIIA) promotes the proliferation of cancer cells, making it a compelling therapeutic target, but it is also significant in other inflammatory conditions. Consequently, suitable inhibitors of hGIIA have always been sought. The activation of phospholipase...

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Detalles Bibliográficos
Autores principales: Kim, Ryung Rae, Chen, Zheng, J. Mann, Timothy, Bastard, Karine, F. Scott, Kieran, Church, W. Bret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583969/
https://www.ncbi.nlm.nih.gov/pubmed/32998383
http://dx.doi.org/10.3390/molecules25194459