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Heteromerization of Endogenous Mu and Delta Opioid Receptors Induces Ligand-Selective Co-Targeting to Lysosomes

Increasing evidence indicates that native mu and delta opioid receptors can associate to form heteromers in discrete brain neuronal circuits. However, little is known about their signaling and trafficking. Using double-fluorescent knock-in mice, we investigated the impact of neuronal co-expression o...

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Detalles Bibliográficos
Autores principales: Derouiche, Lyes, Pierre, Florian, Doridot, Stéphane, Ory, Stéphane, Massotte, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583997/
https://www.ncbi.nlm.nih.gov/pubmed/33007971
http://dx.doi.org/10.3390/molecules25194493