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Gas6 Inhibits Toll-Like Receptor-Mediated Inflammatory Pathways in Mouse Microglia via Axl and Mer

Background: Microglia are well known key regulators of neuroinflammation which feature in multiple neurodegenerative disorders. These cells survey the CNS and, under inflammatory conditions, become “activated” through stimulation of toll-like receptors (TLRs), resulting in changes in morphology and...

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Detalles Bibliográficos
Autores principales: Gilchrist, Shannon E., Goudarzi, Salman, Hafizi, Sassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584110/
https://www.ncbi.nlm.nih.gov/pubmed/33192322
http://dx.doi.org/10.3389/fncel.2020.576650