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Enumerating regulatory T cells in cryopreserved umbilical cord blood samples using FOXP3 methylation specific quantitative PCR

BACKGROUND: Allogeneic haematopoietic cell transplantation (HCT) is a curative therapy for severe haematological disorders. However, it carries significant risk of morbidity and mortality. To improve patient outcomes, better graft selection strategies are needed, incorporating HLA matching with clin...

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Detalles Bibliográficos
Autores principales: Duggleby, Richard C., Tsang, Hoi Pat, Strange, Kathryn, McWhinnie, Alasdair, Lamikanra, Abigail A., Roberts, David J., Hernandez, Diana, Madrigal, J. Alejandro, Danby, Robert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584164/
https://www.ncbi.nlm.nih.gov/pubmed/33095809
http://dx.doi.org/10.1371/journal.pone.0240190